In 2013, she had a recurring role on the FXhorror series American Horror Story: Coven, and was nominated for a Primetime Emmy Award for Outstanding Supporting Actress in a Miniseries or a Movie for her performance as Voodoo queen Marie Laveau. She returned for Freak Show, the anthology series' fourth season, portraying a three-breasted woman named Desiree

Dupree for which she received another nomination for Outstanding Supporting Actress in a Miniseries or a Movie. In 2015, Bassett returned for the fifth seasonAmerican Horror Story: Hotel portraying Ramona Royale, a famous movie star. Bassett has confirmed that she will return for the show's sixth cycle in 2016.